| Group | Club/Team Name | Team ID | Head Coach |
| D21 | Bilu International Soccer Academy BISA 16B Wolves |
03045-001AB9U-2016 | Paulo Copque |
| D22 | Cainhoy Athletic Soccer Club CASC 16 Pumas |
03006-001AB9U-2416 | Patrick Coyle |
| D23 | Cainhoy Athletic Soccer Club CASC 16 Stars |
03006-001AB9U-2403 | Michael Tunesi |
| D24 | James Island Youth SC JIYSC 2016 Boys Red Guice |
03001-001AB9U-0030 | Dylan Guice |
| D25 | South Carolina Surf Soccer Club SC Surf MP 17 Blue |
03008-001AB8U-5699 | Stephen Sweeney |
| D26 | Mt. Pleasant FC - 01 MPFC U9 Firestorm |
03007-001RB9U-0023 | Kevin McNamara |